Microspheres of hydroxyapatite/reconstituted collagen as supports for osteoblast cell growth.
Autor(es):
Hsu FY1, Chueh SC, Wang YJ.
Resumo
Microspheres comprised of particulate hydroxyapatites dispersed in fibrous collagen matrices were prepared. The procedure involved the droplet formation of hydroxyapatite/collagen mixture emulsified in olive oil, followed by the reconstitution of collagen in the presence of hydroxyapatite particles at 37 degrees C. Various sizes of microspheres could be obtained by controlling the stirring speed of the emulsified mixture.